CRCN Inserm, HDR, PhD

Mail : pierre-henri.puech@inserm.fr

Personal page and codes : https://phpuech.github.io/

Boards of Institut Covergence CenTuri (CORES), GDR AQV (COPIL), GDR Imabio (COPIL)

Coordinator of FR/MEX CNRS International Research Project « BioPhysImmuno »

Member of GDR MecaBio, GDR PhyP, SBCF

Brief CV:

Since 2005 : Inserm Researcher (CRCN Inserm since 2009) in Inserm U1067 (Adhesion & Inflammation, Marseille, France), Habilitation / HDR (2009) ; head : Pr. P. Bongrand, now O. Théodoly

2003 – 2005 : post doc in Prof. D. J. Muller’s Group (Dresden, Allemagne) – labs : Biotec, TU-Dresden & Max Planck for Cell Biology and Genetics. Developing single cell force spectroscopy with AFM. Application to cell /cell recognnition in immunology, cancer cell biology and development (collab. CP Heinseberg).

2000 – 2003 : PhD in Soft matter / Biophysics (Univ. Paris VI) in Prof. F. Brochard-Wyart lab : UMR 168 CNRS / Institut Curie (Paris, France). Adhesion and mecanics of giant liposomes (collab. PG de Gennes).

1998 – 2000 : Engineer from ESPCI (Ecole Superieure de Physique et de Chimie Industrielle de la ville de Paris, Paris, France )

1999 – 2000 : Master in Soft Condensed Matter with highest honors (Univ. Paris VI). Adhesion of parasite fungi. Adhesion and rolling of sticky polymeric beads.

Research expertise :

Soft condensed matter. Biophysics. Biology, especially : cell adhesion and mechanics. Immunology. Cell biology. Developmental biology. Force measurements on single molecules or single cells using micropipette, biomembrane force probe (BFP) or atomic force microscopy (AFM) based techniques. Optical microscopy (fluorescence). AFM Imaging. RICM and fluorescence microscopies. Programming (Labview, IgorPro, Python, R, IA : Images, LLM)

Research interests :

T cell mechanotransduction (collaborations Dr. L Limozin & P Robert, Inserm U1067, Marseille ; Dr. Y. Hamon, CIML, Marseille ; K. Sengupta, CINaM, Marseille, Dr. J Husson, LaDHyX Paris, Dr. P. Pierobon, Institut Cochin, Paris, Dr. D. Gonzalez-Rodriguez, U. Metz, JT. Groves, U. Berkeley, USA)

Parasite/Coccidians mechanics, adhesion and interaction with immune cells (collaboration Dr. A Dumètre, Pharmacy Univ, Marseille)

Adhesion and mechanics in pathologies (collaboration N. Bardin, PU-PH, AP-HM/La Timone)

Mechanobiology of fibrosis & cancer (collaboration with Pr. T. Fioderlisio-Coll, UNAM, Mexico-city, Mexico)