Immune effector cell / target cell interactions

L. Limozin, PH. Puech, P. Robert

Collab. P. Chames (CRCM), F. Piazza (Univ. Orléans)


One of our goals is to find rules to design efficient bispecific antibodies targeting effector cells toward tumours. For this we integrate data of single domain antibody kinetics, structural and mechanical properties to improve Antibody Dependent Cell Cytotoxicity by NK cells.


This work receives financial support from Plan Cancer – Physcancer program.