Annual scientific day of Aix-Marseille University Imaging Institute took place February 23rd. Laureates of the 2023 call for interdisciplinary projects presented the progress of the past year of their respective projects. Among them, a collaborative project gathering Julien Lumeau, Fabien Lemarchand, Antonin Moreau from Fresnel Institute in Marseilles and Marie-Pierre Valignat, Olivier Theodoly and Philippe Robert from LAI was presented. It focuses on coupling micropatterned cellular assays from LAI to anti-reflexive surfaces produced by Fresnel Institute to detect protein secretion by cells, to obtain marker-less, manipulation-less and real-time assays adapted to routine hospital use.