Olivier Theodoly presented the results of the IMMUNOCHIP project, selected for funding through the 2024 Cancéropôle Maturation call. The project sought to demonstrate the technological feasibility of novel diagnostic microdevices designed to guide cancer immunotherapy through the functional profiling of immune cells. Prototype tests were developed and evaluated to assess the activation and functional responses of T cells, CAR-T cells and NK cells.

https://canceropole-paca.com/agenda/seminaire-annuel-2023-du-canceropole-provence-alpes-cote-dazur/

We are pleased to share that members of the LAI took part in the European South Atlantic Biophysics Conference 2026, held from 17 to 19 June 2026 in Montpellier.

Arnauld Sergé presented a poster entitled “Nanodynamics and blockade of RANK/RANKL interactions between leukemic and thymic epithelial cells”, a collaborative work with Loriane Maillot, Martine Biarnes-Pelicot, Magali Irla.

Pierre-Henri Puech was invited as a speaker and gave a talk entitled “Some aspects of T cells mechanobiology”.

Many thanks to the organisers for a stimulating meeting.

We are pleased to share that Arnauld Serge, from our lab, led a project at the 2026 CENTURI Hackathon, held from 5 to 7 June at the Villages Clubs du Soleil in La Belle de Mai, Marseille, an event dedicated to coding, engineering, and idea-sharing at the interface of computer science and the life sciences. Together with Magali Irla, Arnauld proposed and led Thymo3D: mapping thymic architecture to decode immune health, which set out to reconstruct the mouse thymus in three dimensions and quantify how its structural organisation relates to immune health and disease. This year’s edition brought together 36 participants across six interdisciplinary projects. Many thanks to Philippe Roudot, Léo Guignard, and the CENTURI team for organising such a stimulating event.

Olivier Theodoly presented the MOHICAN, laureate of the PEPR MED-OOC call 2025. The MOHICAN project aims to develop new medical devices enabling functional testing of patient immune cells as part of routine hospital practice. These innovative devices will integrate microfluidic components coupled with microprinted molecular patterns to recreate structures that mimic secondary and tertiary lymph. The MOHICAN consortium brings together leading biophysics teams (LAI – Marseille and IINS – Bordeaux), clinical partners from AP-HM and IPC, as well as the TAGC genomics laboratory.

https://www.pepr-medooc.fr/projet/micropuces-pour-lanalyse-personnalisee-des-fonctionsimmunologiques-en-oncologie-clinique-de-routine-mohican

We are pleased to share that members of the LAI attended the GdR AQV Days 2026, the annual meeting of the CNRS GdR “Approches Quantitatives du Vivant”, held in Aussois from May 11 to 13, 2026.

The meeting offered a valuable opportunity to follow current work in the quantitative approaches to living systems community, exchange ideas, and discuss shared research questions with colleagues from different backgrounds.

Pierre-Henri Puech, Marie Dessard, and Jana El Husseiny took part in the conference. Jana also presented her PhD work in a selected talk, contributing to the scientific discussions during the meeting. Pierre-Henri was also involved in the organisation of the event.

Many thanks to the organisers and participants for making this a stimulating and enjoyable meeting.