Cell self-steer like single-handed circumnavigators

The mechanism of lymphocytes guiding against a flow was shown to use the tail of lymphocyte like a wind vane in a breeze. This wind vane self-steering system is reminiscent ofa system used by sailors to orient their ship with the wind.

This interdisciplinary work between physics, biology and yachting was published in Nature communication: “Lymphocytes can self-steer passively with wind vane uropods” By:Valignat, MP, Negre, P, Cadra, S, Lellouch, AC, Gallet, F, Henon, S, Theodoly, O;NATURE COMMUNICATIONS, 5, 5213, DOI: 10.1038/ncomms6213, OCT 2014.

See also on the CNRS web site (INP ‘Actualités)

http://www.cnrs.fr/inp/spip.php?article3137

Welcome to our new PhD students Yoon & Alex

This month, Yoon Koo and Alexander Hornung have started their PhD projects.

Yoon comes from Korea. She will be supervised by Anne-Marie Lellouch and Jean-Pierre Gorvel in a Labex inform project involving also Marie-Pierre Valignat and Olivier Theodoly. The goal is to develop study the migration properties of T lymphocytes subpopulation generated by the infection of mice by Bordetella Perrtussis.

Alexander comes from Austria. He will be supervised by Marie-Pierre Valignat and investigate the properties of lymphocyte migration on substrates with different adhesion properties.

A new research assistant (Ingénieur d’Etudes) in LAI!

Martine Pelicot starts her new job in LAI. Martine has 4 years’ experience in a private company, VIRBAC and was then hired by INSERM in Paris, in unit U699 Immunopathologie Rénale, Récepteurs et Inflammation. She is now temporarily hosted at LAI as a research assistant.  Martine will be in charge of producing new types of engineered cells, with her background of molecular biology and flow cytometry skills.