The group of Tam Mignot, with which O. Theodoly has been collaborating for 10 years, is pursuing his leading research activity on the mechanisms of micro-organisms motility. A novel paper in the journal Nature with association of LAI for technical support on microscopy experiments has just been published: “The mechanism of force transmission at bacterial focal adhesion complexes”, Volume: 539, Issue: 7630, Pages: 530, DOI: 10.1038/nature20121, Published: NOV 24 2016.
Article
A new article on bacteria adhesion & motility
Laura Faure, Jean Bernard Fiche, Leon Espinosa, Adrien Ducret, Jennifer Luciano, Sébastien Lhospice, Salim Islam, Julie Tréguier, Erkin Kuru, Yves Brun, Olivier Théodoly, Marcelo Nollmann, Tâm Mignot (2016) The mechanism of force transmission at bacterial focal adhesion complexes. Nature. 539(7630):530-535.
Laminar flow chamber 2.0 in Scientific Reports
We published the first paper obtained with our in-house designed and built laminar flow chamber automation. This innovative machine allows fast single molecular force studies, for both kinetics and thermodynamic studies. Please see: A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation. Sci Rep. 2016 Oct 12;6:35193.
A new article on single bond physics in Scientific Reports
A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation. Limozin L, Bongrand P , Robert P (2016) Sci. Rep. 6:35193
A new article on Toxoplasma vs. macrophage in Scientific Reports
Freppel W, Puech PH, Ferguson DJP, Azas N, Dubey JP, Dumètre A (2016) Macrophages facilitate the excystation and differentiation of Toxoplasma gondii sporozoites into tachyzoites following oocyst internalisation. Sci Rep. 2016 Sep 19;6:33654
A new article on advanced optical techniques in Lab Chip
Huerre A, Jullien MC, Theodoly O, Valignat MP (2016) Absolute 3D reconstruction of thin films topography in microfluidic channels by interference reflection microscopy. Lab. Chip. 16:911-916, doi 10.1039/C5LC01417D
A new article on cell mechanics in Scientific Reports
Guillou L, Babataheri A, Puech PH, Barakat AI, Husson J (2016) Dynamic monitoring of cell mechanical properties using profile microindentation. Sci. Reports 6:21529.
A new article on spreading on nanostructured surfaces
Dillard P, Pi F, Lellouch AC, Limozin L, Sengupta K (2016) Nano-clustering of ligands on surrogate antigen presenting cells modulates T cell membrane adhesion and organization. Integrative Biology 8:287.
A new article on SDRA / microfluidics
Preira P, Forel J-M, Robert P, Nègre, Biarnes M, Xeridat F, Bongrand P , Papazian L, Théodoly O (2016) The leukocyte stiffening property of plasma in acute respiratory distress syndrome (ARDS) revealed by microfluidic single-cell study: role of cytokines and protection with antibodies. Critical Care 20 : 8.
A new article on medical applications
Bertin D, Mouhajir Y, Bongrand P, Bardin N (2016) ICARE improves antinuclear antibody detection by overcoming the barriers preventing accreditation. Clinica Chimica Acta 454 : 57-61.
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