Laurent Limozin was invited to present at the event ‘AI & Imaging for Cell and Developmental Biology: Insights, Limits and Perspectives,’ held on September 26, 2024, in Paris. This event, organized by the BCDE Institut thématique INSERM, explored the role of artificial intelligence and imaging techniques in advancing research in cell and developmental biology.
We are excited to announce that several members of our laboratory participated in the 18th edition of the Physics of Living Matter Conference (PLM 18), held on September 16-17, 2024, at the Palais du Pharo, Marseille. This prestigious international symposium, organized by CENTURI – Turing Centre for Living Systems, gathered interdisciplinary scientists from all over the world to explore the interface between physics and biology.
Laurent Limozin, Florian Dupuy, Arnauld Serge, Gaurav Verma, Jana Elhusseiny, Ahmad Awada, and Lorna Ammer attended the event. During the poster sessions, Arnauld, Ahmad, Jana, and Gaurav presented their research through poster presentations.
The conference featured a vibrant environment for scientific exchange and collaboration. We are thrilled to have been a part of this inspiring event and look forward to contributing to future editions.
We are pleased to share that Chandrasekar Subramani Narayana recently participated in the LIS (Laboratoire d’Informatique et Systèmes) PhD Students Day on June 7, 2024. He presented his work titled “Counting Phage: Decoding Antibody & Antigen Kinetics Behavior,” which focuses on the counting task in fluorescence microscopy images and count-guided localization using deep learning and computer vision.
The event offered a valuable opportunity for sharing scientific interests and knowledge while discovering the diverse range of topics being explored by other PhD students and research teams.
We are excited to announce that Aurélien Dumètre and Jana El Husseiny recently attended the 17th International Toxoplasmosis Conference in Berlin, Germany. This event covered various aspects of Toxoplasma research, ranging from molecular biology to clinical disease and epidemiology.
Before the main conference, they participated in the 3rd Environmental Toxoplasmosis Meeting, co-organized by Aurélien Dumètre and other experts in the field. This meeting focused on advancing the understanding of the environmental aspects and public health implications of Toxoplasmosis. Additionally, they attended a joint session with the ToxoDB workshop, which aimed to enhance participants skills and knowledge in using the ToxoDB database for research and data analysis.
Aurélien gave a talk at the workshop titled “Eimeria acervulina, a Promising Surrogate for the Study of Toxoplasma gondii Oocyst Inactivation.” Jana showcased her PhD project at both the workshop and the conference, delivering a talk at the workshop and presenting a turbo talk and a poster on her research titled “Unraveling Morphological and Biomechanical Responses to Harsh Environmental Conditions in Coccidian Oocysts.”
We are proud of their contributions and the recognition of their work at these significant scientific gatherings.
We are pleased to share that Ahmad Awada delivered an insightful presentation titled “Effects of Adhesion and Confinement on Leukocyte Migration” at the CENTURI – Turing Centre for Living Systems scientific day: Success Stories and New Horizons, held on May 30th at Jardins du Pharo.
The event was a remarkable gathering, bolstering the community spirit through networking and the sharing of ideas and future outlooks. It provided an excellent platform for researchers to connect, collaborate, and envision new horizons in scientific research.
On the 4th of April 2024, Rémy Torro, Ph.D. successfully defended his work titled “High throughput analysis of dynamic single cell interactions imaged by multimodal optical microscopy” in front of a jury composed of experts in the field, Alice Nicolas, David Rousseau, Daniel Sage, Loïc Dupré under the supervision of Laurent Limozin and Kheya sengupta. His work focused on develloping a software called Celldetective to describe complex cell interactions from multimodal microscopy images, leveraging recent AI techniques and applying it to test cell engagers for immunotherapy in cell-surface and cell-cell interaction assays.
Celldetective is now available and free to use on GitHub: https://lnkd.in/dGpj_UUx
Best of luck, Remy!
In association with CENTURI – Turing Centre for Living Systems
We are excited to share our latest research published in the International Journal of Molecular Sciences: “Comparison of the Capacity of Several Machine Learning Tools to Assist Immunofluorescence-Based Detection of Anti-Neutrophil Cytoplasmic Antibodies.”
This work was conducted in collaboration with Daniel Bertin and Nathalie Bardin, both members of the Immunology Laboratory of Marseille Hospitals, and Pierre Bongrand from LAI.
This study addresses a current challenge of using artificial intelligence to perform biomedical tasks without any human intervention, which might result in lower cost, increased availability and increased rapidity. Here, we compared the capacity of several widely available machine learning tools to analyze microscopic images in order to diagnose some autoimmunity diseases. The paper described preliminary results obtained with a dataset of 1,733 cell images.
For more information, visit the publication: https://doi.org/10.3390/ijms25063270.
Annual scientific day of Aix-Marseille University Imaging Institute took place February 23rd. Laureates of the 2023 call for interdisciplinary projects presented the progress of the past year of their respective projects. Among them, a collaborative project gathering Julien Lumeau, Fabien Lemarchand, Antonin Moreau from Fresnel Institute in Marseilles and Marie-Pierre Valignat, Olivier Theodoly and Philippe Robert from LAI was presented. It focuses on coupling micropatterned cellular assays from LAI to anti-reflexive surfaces produced by Fresnel Institute to detect protein secretion by cells, to obtain marker-less, manipulation-less and real-time assays adapted to routine hospital use.
We are delighted to inform you that our engineer, Martine Biarnes Pelicot, has contributed to the book “Etonnante physique” published by CNRS. In her article, Martine explains how genetic engineering enables her to create tailor-made tools for studying the biophysics of immune cells.
This book brings together 70 contributions from physicists who have recently been awarded a CNRS medal. The book offers a captivating exploration of the many areas covered by this surprising discipline. It is designed to be accessible to all those who are curious about science.
We invite you to discover this fascinating book by following the link below: https://anneedelaphysique.cnrs.fr/ressource/etonnante-physique/”
We are delighted to share the remarkable achievement of Valentine Seveau de Noray, who has been honored with the “Accessit au prix Daniel Guinier” for the year 2022. This prestigious award is presented annually by the French Physical Society (SFP) to young physicists for their exceptional research during their doctoral studies.
Valentine’s dedication and innovative contributions to the field have earned her a second prize, a testament to her unwavering commitment to advancing scientific knowledge. Valentine finished her thesis “Quantitative study of cell guidance in controlled microenvironments: atypical cases of rheotaxis and adhesive haptotaxis” under the guidance of Olivier Theodoly and Marie-Pierre Valignat.
Congratulations, Valentine!
For more details on Valentine’s research and the award, please visit the link below: http://sfpnet.fr/baptiste-bienvenu-et-valentine-seveau-de-noray-accessits-aux-grands-prix-de-these-2022-de-la-sfp
Adhesion & Inflammation Lab 
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