One more Dr at LAI!

Yet another summer that ends with the graduation of a new PhD. Nicolas Garcia Seyda joined the lab as an engineer before deciding to pursue his PhD in the sunny city. He successfully defended his thesis entitled “Live imaging of leukocyte migration in controlled in vitro setups”. His presence in the lab is surely going to be missed, we wish him the best on his new adventures!

New PhDs at LAI!

LAI is happy to welcome the new batch of PhDs joining us this year.

Valentine Seveau will be using micro-fluidic techniques and micro-patterning technologies (PRIMO Alveole) to study the guidance of T cell lymphocytes mediated by integrins and cellular adhesion molecules on a substrate, also known as haptotaxis. She’ll be co-directed by Olivier Théodoly and Marie-Pierre Valignat.

Elodie Lafargue will be trying to characterize for the first time the rest structure of voltage-dependent channels at the molecular level as well as the dynamics of electrical signal transduction when opening or closing the transmembrane channel thanks to two novel breakthroughs in High-Speed Atomic Force Microscopy (HS-AFM) technology. Elodie will be supervised by Ignacio Casuso.

Rémy Torro and Lama Awada also joined us through the CENTURI PhD program. Rémy will be co-directed by Laurent Limozin at LAI and Kheya Sengupta at CINAM, he’ll be using reflection interference contrast microscopy (RICM) and deep learning-based techniques, as a systematic approach to perform 3D reconstructions of cell membranes at the interface with substrates. Lama on the other hand, is supervised by Philippe Robert at LAI and Pierre Milpied at CIML and she’ll be trying to characterize the nature of physical cues driving antibody affinity maturation in B cell immune responses using the laminar flow chamber in 2D while simultaneously integrating parallel analysis of transcriptome and antibody genes sequences at single-cell resolution.

Welcome everyone and we wish you a successful journey!

LAI welcomes new postdoc!

Dalia El Arawi started her LAI journey during COVID19 lockdown on the physical and computational aided design of bispecific antibodies for cancer immunotherapy under the supervision of Laurent Limozin. Her main objective will consist of testing bispecific antibodies using in vitro Antibody Dependent Cell Cytotoxicity mediated by NK cells employing TIRFM and RICM.

LAI welcomes new PI!

The lab is excited to have Arnauld Sergé joining its researchers staff. Arnauld is an associate professor in Biology and Physics at AMU. His research is centered on membrane dynamics using single-molecule microscopy and image analysis, with his current project focusing on « Dynamic videonanoscopy of immuno-cancer interactions ».