Microfluidics, cell rheology and medical transfer

labadhesioninflammationsite Article

The long term effort to develop microfluidic tools to probe the rheological properties of circulating leukocytes has allowed getting new insight in the triggering mechanisms of the acute respiratory distress syndrome. This work, performed in a collaboration with Dr Forel and Pr Papazian from AP-HM has been published in Critical Care:  “The leukocyte-stiffening property of plasma in early acute respiratory distress syndrome (ARDS) revealed by a microfluidic single-cell study: the role of cytokines and protection with antibodies”

Critical Care  (2016) 20:8 DOI 10.1186/s13054-015-1157-5

Welcome Marie-Julie

labadhesioninflammationsite Lab life

Marie-Julie DEJARDIN is doing her Master 2 internship for 6 months, in the frame of the Nice University Imaging Program. She is financially supported by GDR MIV and will work on imaging APC lamellipods with combined AFM and interferometry under the direction of Pierre-Henri Puech and Laurent Limozin.

The project ‘Recrute’ has been awarded by ANR

labadhesioninflammationsite Lab life

This project intends to perform quantitative analysis of some essential steps of the leukocyte recruitment cascade using in vitro tools developed at LAI based on microfluidics and protein patterning. The in vitro approach will be based on and compared with in vivo models of T cell traffic in lymph node, T cell response to infection by Bordetella pertussis, and T cell properties of patients with multiple sclerosis. This project is a LAI collaboration with Alveole company (Luc Talini, Romuald Valy), Vincent Studer (IINS, Bordeaux), Claire Hivroz (Institut Curie, Paris) Marc Bajénoff and Jean-Pierre Gorvel (CIML), as well as Philippe Robert and Audrey Ricco (AP-HM).

External seminars, < 2016

phpuech Seminar

meeting-1-e1454592025383

2015
4/12/2015    Anna Labernardie (Barcelone, Spain)
27/11/2015    Giovanni Cappello (Liphys, Grenoble)
26/11/2015    Pierre Mangeol (IBDML, Marseille)
20/11/2015    Sébastien Sart (Ladhyx, Palaiseau)
19/11/2015    Jérôme Hottin (CBS, Montpellier)
16/11/2015    Andrey Zavialov (Turku, Finland)
6/11/2015    Martial Balland (Liphy, Grenoble)
16/10/2015    Cécile Bidan (Liphy, Grenoble)
29/9/2015    Demosthène Mitrossilis (Institut Curie, Paris)

2014
12/12/2014    Guillaume Gay (DAMCB, Marseille)
5/12/2014    Adrien Ducret (Indiana Univ., USA)
24/11/2014    Clemens Franz (Karlsruhe, Germany)
7/11/2014    Sylvain Gabriele (Mons, Belgium)
12/9/2014    Karine Anselme (IS2M, Mulhouse)
13/6/2014    Guillaume Voisinne (CIML, Marseille)
6/6/2014    Daniel Jost (ENS Lyon)
14/5/2014    Lena Svensson (Lund, Sweden)
12/5/2014    Cyrille Mionnet (Gand, Belgium)

2013
18/10/2013    Claire Hivroz (Institut Curie, Paris)
6/9/2013    Lionel Foret (LPS, Paris)
6/6/2013    Arnaud Millet (Institut Cochin, Paris)
24/5/2013    Julien Textoris (APHM, Marseille)
25/1/2013    Aurélien Dumètre (AMU, Marseille)

2012
14/12/2012    Salvatore Valitutti (Centre Physiologie, Toulouse)
15/10/2012    François Robin (Chicago, USA)
12/10/2012    Dimitri Missirlis (Heildeberg, Germany)
12/7/2012    Zhan Hua Silber Li (Beijing, China)
15/6/2012    Abdul Barakat (Ladhyx, Palaiseau)
23/3/2012    Delphine Muriaux, Cyrille Favard (CPBS, Montpellier)

2011
29/9/2011    Ulrich Blank (Inserm Bichat, Paris)
01/7/2011    Atef Asnacios (MSC, Paris)
10/6/2011    Catherine Even (LPS, Orsay)
13/5/2011    Patricia Veras, Washington Dos Santos  (Salvador, Brasil)
18/3/2011    Marc Bajenoff (CIML, Marseille)