Dalia El Arawi started her LAI journey during COVID19 lockdown on the physical and computational aided design of bispecific antibodies for cancer immunotherapy under the supervision of Laurent Limozin. Her main objective will consist of testing bispecific antibodies using in vitro Antibody Dependent Cell Cytotoxicity mediated by NK cells employing TIRFM and RICM.
The EMBO workshop on Immunobiophysics in Les Houches has been postponed to 14–19 March 2021 with the same exceptional speaker list, and at the same amazing location!
Please stay tuned here and/or on the official EMBO Website/Letters for more information soon!
The organizing Committee is composed of:
Pierre-Henri Puech (Chair, LAI, Marseille), Katelyn Spillane (King’s College, London), Julien Husson (LadHyX, Polytechnique, Orsay), Laurent Limozin (LAI, Marseille), Jérémie Rossy (University of Konstanz, Kreuzlingen).
For more info: https://meetings.embo.org/event/20-immunobiophysics
& find us on Twitter @ImmunoBiophys
The lab is excited to have Arnauld Sergé joining its researchers staff. Arnauld is an associate professor in Biology and Physics at AMU. His research is centered on membrane dynamics using single-molecule microscopy and image analysis, with his current project focusing on « Dynamic videonanoscopy of immuno-cancer interactions ».
Thanks to the co-financing of S. Spicuglia (U1090) and a mutual request of the units to the region (U1067-U1090-U1097), the common cell culture platform of the building has recently acquired:
- a sorter BD FACSMelody: 3 lasers, 9 colors and single-cell module
- a BD LSRFortessa X20 cell analyser : 3 lasers, 14 colors
Lorenzo Villanueva joined the lab in March 2019 and he will work under supervision of Felix Rico on developing LabVIEW software as interface for High Speed AFM. Welcome Lorenzo!
Jorge Rodriguez Ramos joined the lab in November 2018, while Claire Valotteau and Luca Piantanida in January 2019. Jorge is working on the project “ Multi-scale mechanics of dynamic leukocyte adhesion ” and Claire is working on “Evolutionary mechanics of adhesion complexes” project both with Felix Rico. Luca Piantanida works with Ignacio Casuso on “Protein-induced lipids partitioning and cell mechanical properties influenced by Salmonella infection”. Welcome!
A new review on the toxoplasma walls was just published in collaboration
with A. Dumetre from IHU, Marseille. In this review, we highlight how
the oocyst and sporocyst walls sustain the persistence and transmission
of infective T. gondii parasites from terrestrial and aquatic
environments to the host. We further discuss why targeting the oocyst
wall structure and molecules may reduce the burden of foodborne and
waterborne T. gondii infections.