Reflection interference contrast microscopy (RICM), permits imaging and measuring with its ability to measure inter-surface distances under water with nanometric precision and milliseconds time resolution without sample labelling It is ideally suited to studying dynamical adhesion processes in soft matter and cell biology (Limozin 2009).

Original developments an applications in the lab include accounting for polarisation effects in a complete reconstruction model (Theodoly 2010), as well as reconstuction of droplets in channels (Huerre 2016), and lamellipods of spread cells (Dejardin 2018).


Limozin L, Sengupta K (2009) ChemPhysChem 10: 2752-2768. Pubmed

Theodoly O, Huang Z H, Valignat M-P (2010) Langmuir 26: 1940-1948. Pubmed

Huerre A, Jullien MC, Theodoly O, Valignat MP (2016). Lab. Chip. 16:911-916. Pubmed

Dejardin MJ, Hemmerle A, Sadoun A, Hamon Y, Puech PH, Sengupta K, Limozin L (2018) Nano letters, 18:6544-6550. Pubmed