CENTURI Scientific Day 2025!

We are pleased to share that Jana El Husseiny presented her work “Unraveling Morphological and Biomechanical Responses to Stressors in Coccidian Oocysts”, and Gaurav Verma gave a flash talk titled “Molecular Geometry Controls Immune Response” at the CENTURI – Turing Centre for Living Systems Scientific Day, held on September 17th at Jardins du Pharo.

The event brought together current members and alumni, fostering networking, idea exchange, and discussions on future perspectives. The day concluded with a convivial cocktail evening at Villa Gaby.

LAI celebrated its newest Dr !

On the 16th of september 2025, Chandrasekar Subramani Narayana successfully defended his work titled “Deep learning-based counting and binding kinetics of bacteriophages imaged by fluorescence microscopy“, under the supervision of Laurent Limozin and Stéphane Ayache. This achievement was presented to a distinguished panel of experts in the field, including Laurent Vonna, Rémi Eyraud, Guillaume Gay and Cécile Capponi,

LAI wishes you all the best for the rest of your career, full of success, and thanks you for your hard work and the positive energy you shared within the laboratory.

Bye bye CS !!

A new article “Quantitative Microscopy for Cell–Surface and Cell–Cell Interactions in Immunology”

We present a detailed protocol for conducting high-content microscopy assays of immune cells interacting with antigen surfaces and antigen-presenting cells. The principle of the method is illustrated by redirecting NK cells on HER2 antigens using original bispecific antibodies. We provide a complete analysis pipeline using our open-source, home-made software, Celldetective.

🔗 Article

LAI celebrated its newest Dr !

On the 23th of June 2025, Luc David Broglio successfully defended his work titled “Outils diagnostics pour l’immunologie basés sur la micro-impression d’anticorps“, under the supervision of Olivier Theodoly and Philippe Robert. This achievement was presented to a distinguished panel of experts in the field, including Charlotte Riviere, Sylvain Gabriele, Régis Costello, Sophie Asnacios and Vincent Studer.

We thank Luc for his dedicated work developing microchips printed with multiple functional proteins to measure the kinetics of leukocyte activation at the single-cell level. The entire lab warmly congratulates Luc for this important milestone and wishes him continued success in his future scientific endeavors!

External Seminar: Jay Groves’s

We were delighted to host Jay Groves from the University of California, Berkeley, during his recent visit to Marseille. He was warmly welcomed by Pierre-Henri Puech (LAI) and Kheya Sengupta (CINaM). As part of the CENTURI Seminar Series, Jay Groves delivered a captivating talk titled:
“Phase transitions, mechanics, and stochastic timing in signal transmission from single T cell receptors.” His visit sparked rich and stimulating discussions on T cell activation, biomolecular condensates, and the biophysics of immune signaling, fostering valuable exchanges across multiple research teams. It was a real pleasure to welcome him and engage in thought-provoking conversations at the intersection of physics and immunology.
We extend our sincere thanks to Jay Groves for his inspiring visit and contribution.

Les Athlètes Improbables Take on La Marseillaise des Femmes for the Third Time!

We’re proud to share that our lab team, “Les Athlètes Improbables,” has marked their third consecutive participation in La Marseillaise des Femmes! With the support of INSERM, our runners took on this empowering race in solidarity with women’s rights and breast cancer research.

After months of training, the team once again displayed exceptional determination, teamwork, and spirit. The tradition continues, along with our weekly runs through the beautiful trails of the Calanques.

Congratulations to all participants!

Les Houches: Immunobiophysics EMBO workshop 2025

Building on the success of the virtual (2021) and hybrid (2023) events, the third edition of the hybrid workshop on ImmunoBiophysics: From Fundamental Physics to Understanding the Immune Response took place from 27 April to 2 May 2025 in Les Houches, France.

This year’s workshop focused on immune cell regulation from a distinctly physical and mechanical perspective, with the aim of advancing opportunities for translational impact in human health and disease.

In our laboratory, Pierre-Henri Puech, one of the co-organizers, opened the conference with a foundational talk on immunobiophysics. Philippe Robert was among the invited speakers and delivered a presentation titled “CD16 Transmits Defined Piconewton Forces During Natural Killer Cell Activation.” Our Ph.D. student, Gaurav Verma, also contributed to the event by presenting a poster on his current research project titled “Edit-T-cell Spreading Dynamics Mediated by New Bispecific Agents“.

For more information, please visit: https://meetings.embo.org/event/25-immunobiophysics

Centuri Retreat 2025 !

Five PhD students from our lab, Jad Sleiman, Gaurav Verma, Ahmad Awada, Marie Dessard and Jana El Husseiny participated in the recent CENTURI retreat, held in Gorges du Verdon from April 23 to 25, 2025. The event brought together PhD students and postdocs for a diverse program of scientific exchange, skill-building workshops, and outdoor activities. Attendees took part in sessions ranging from microscopy and debating to kayaking and astronomy, all designed to strengthen our academic community.

We extend our sincere thanks to the CENTURI organizing and administrative committees for making this event possible.

Photo credits: Rémi Wojciechowski – CENTURI