We were delighted to host Jay Groves from the University of California, Berkeley, during his recent visit to Marseille. He was warmly welcomed by Pierre-Henri Puech (LAI) and Kheya Sengupta (CINaM). As part of the CENTURI Seminar Series, Jay Groves delivered a captivating talk titled:
“Phase transitions, mechanics, and stochastic timing in signal transmission from single T cell receptors.” His visit sparked rich and stimulating discussions on T cell activation, biomolecular condensates, and the biophysics of immune signaling, fostering valuable exchanges across multiple research teams. It was a real pleasure to welcome him and engage in thought-provoking conversations at the intersection of physics and immunology.
We extend our sincere thanks to Jay Groves for his inspiring visit and contribution.
Seminar
TPR2 INSERM Meeting
On January 10, 2025, a half-day “TPR2 Inserm Meeting” at Hexagone, was held to bring together the four single-teams and shared services housed in TPR2 building.
This convivial event gave the building’s staff the opportunity to meet each other and consider new opportunities for collaborations.
The event ended with a traditional “Galette des rois”.

External Seminar: Cyril Favard’s Insightful Talk on HIV-1 assembly in living T cells
We are pleased to share that on 16 October, Cyril Favard from the Institut de Recherche en Infectiologie de Montpellier (IRIM) delivered a talk entitled “Mechanics and Kinetics of HIV-1 Assembly in Living T Cells: Insights from Single/Few Molecule Dynamics.”
We extend our heartfelt thanks to Cyril Favard for his insightful presentation.

External Seminar: Katelyn Spillane’s Insightful Talk on B Cell Activation
We are excited to highlight a key moment from our June 28th seminar. Katelyn Spillane from the Department of Life Sciences at Imperial College London delivered a fascinating presentation titled “Physical Regulation of B Cell Activation in the Immune Synapse.” She explored the intricate mechanisms behind B cell activation within the immune synapse.
Her talk captivated the audience, featuring an interactive Q&A session that encouraged deeper exploration and discussion of the latest research findings.
We extend our heartfelt thanks to Katelyn for her valuable contribution.

External seminar: Shalini Low-Nam
Prof. Shalini Low-Nam “Molecular thresholds for T cell activation” (coorganized with CINAM) CIML
External seminar: Jochen Guck
Prof. Jochen Guck “High throughput mechanical phenotyping for in vitro diagnostic” (coorganized with Centuri) Hexagone
Scientific guest at LAI!

We are happy to welcome Ramray Bhat, from IISc Bangalore this week! He is using both experimental and theoretical methods in order to understand how form changes or remains unchanged in physiological and pathological contexts. His research work focuses on cellular reorganization within the contexts of breast and ovarian cancer metastasis. By employing both experimental and theoretical approaches using simulations and bioinformatics, he aims to build experimentally motivated frameworks to understand their multiscale dynamics.
We are starting a collaborative project and are very excited to build new science together!
Ramray Bhat will give a talk entitled Unravelling interactive frameworks of cellular collectives in cancer migration on April, 3rd!
External seminar: Frauke Gräter
Prof. Frauke Gräter “From mechanical to oxydative stress” (coorganized with Centuri) Hexagone
External seminar: Anna Labernadie
Dr. Anna Labernadie “From mechanobiology to bioengineering approaches: addressing the role of the tumor microenvironment in cancer spreading and immunotherapy outcomes” Amphi 12


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