LAI PhD student Xuan Luo participated in the Biointerface 2018 confererence from Aug.13rd-16th and presented a poster on “In vitro quantitative study of T cell adhesive haptotaxis”. Congratulations!
LAI member Arin Marchesi published in Nature Communication
LAI member Arin Marchesi in collaboration with Simon Scheuring (Cornell University, NY) published in Nature Communication on cyclic nucleotide-gated channels dynamics using high-speed AFM.
https://www.nature.com/articles/s41467-018-06414-8#article-info
Congrats!
LAI member Ignacio CASUSO among keynote speakers at Imaging Life 2018: Postgraduate Symposium
LAI member Iganacio Casuso gave lecture at Imaging Life 2018 Post graduate Symposium at the Diamond, University of Sheffield.
LAI member Felix Rico gave lectures at international conferences
On 29 August 2018, Felix gave a lecture at the 14th Greta Pifat-Mrzljak International School Biophysics in Split, Croatia.
On 10 September 2018, Felix presented a seminar at the International Microscopy Congres in Sydney, Australia.
LAI members partner in new ANR funding
LAI is partner of the new ANR funding “Nano-thick liquid films: dynamic and stability of diphasic systems” with Olivier Theodoly, Marie-Pierre Valignat and Martine Biarnes from LAI and Marie-Caroline JULLIEN, coordinator (Institut Pierre Gilles de Gennes, Paris), Lydéric BOCQUET (Ecole Normale Supérieure, Paris) and Annie COLLIN (Ecole supérieure de Physique et Chimie de Paris).
Congratulations!
LAI member files new patent with collaborators!
A new patent “chitosan films and their use for the adhesion of microorganisms” was recently filed by Olivier THEODOLY from LAI, Tam MIGNOT (Laboratoire de chimie bactérienne, Marseille), Guillaume SUDRE and Laurent DAVID (Institut des matériaux polymères, Lyon).
Congratulations!
PhysCancer funding obtained by Laurent Limozin and LAI collaborators.
The project “Physical and computational aided design of bispecific antibodies for cancer immunotherapy” will be lead by LAI member Laurent Limozin in collaboration with P. Chames (CRCM, Marseille) and F. Piazza (CNRS, Orléans).
Congratulations!
LAI members publish in Nanoletters!
LAI members Laurent Limozin, Anaïs Sadoun and Pierre-Henri Puech and former trainee Marie-Julie Dejardin recently published in Nanoletters (IF=12) on Lamellipod Reconstruction by Three-Dimensional Reflection Interference Contrast Nanoscopy (3D-RICN). You can read the paper here: https://pubs.acs.org/doi/ipdf/10.1021/acs.nanolett.8b03134.
Congratulations !
LAI welcomes new visiting students!
LAI will have two upcoming visiting students:
Eider Nunez Viadero who comes from the Biofisika institute in Bilbao (Spain).
She will stay for three months, till December 3rd, and do high speed AFM on a potassium channel with Arin Marchesi.
Clotilde Nodet, pharmacy students in her fifth year, will be doing a part-time six month elective until february 28th. She will work on effect of Natalizumab on lymphocyte adhesion and migration with Olivier Théodoly, Marie-Pierre Valignat and Philippe Robert in La Conception.
Welcome!
A new article on three-dimensional reconstruction of the cell lamellipod without need of fluorescent labelling by using Interferential Nanoscopy in Nano Letters
Long-time expertise of LAI (in collaboration with CINAM) in Reflection interference contrast microscopy have recently permitted a new advance to perform nanometer scale mapping of the cell lamellipod in vitro. Combining multicolor RICM with in silico reconstruction and using optical modeling, the topography of the upper and lower membrane of a lamellipod was reconstructed, as well as the refractive index mapped. These measurements were successfully compared with independent determinations using Atomic Force Microscopy or Quantitative Phase Imaging which both provide only a partial information.
https://doi.org/10.1021/acs.nanolett.8b03134
3D representations of basal membrane (left: seen from under) and of apical membrane (right : seen from top).


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